Factory Supply Amorolfine Hydrochloride CAS 78613-38-4 Amorolfine HCl Powder Antifungal

• Customization: Available
• Powder: Yes
• Certification: GMP, Cep
• Model NO.: Amorolfine Hydrochloride
• Suitable for: Adult
• State: Solid
• Quality: High
• Colour: White Powder
• MOQ: 1 Kilograms
• Storage: Cool Dry Place
• Package: 1kg/Bag, 25kg/Drum
• Delivery Time: 15-25 Days
• Use: Medicine
• Place of Origin: Anhui, China
• Advantage: Fctory & Professional
• Brand Name: Keynovo
• Shelf Life: 2 Years
• Sample: Avaliable
• Transport Package: Safe Packing
• Trademark: keynovo
• Origin: China
• Production Capacity: 50000 Kg Per Week

Product Description

Product Description

Product Description:
Amorolfine Hydrochloride is a synthetic antifungal agent, specifically formulated for topical use. It is a white to off-white crystalline powder with high purity (>99%), synthesized under strict pharmaceutical-grade conditions to ensure stability and efficacy. Amorolfine Hydrochloride is highly lipophilic, enabling deep penetration into keratinized tissues such as nails and skin. It is soluble in organic solvents and compatible with nail lacquers, creams, or gels for targeted delivery. Compliant with pharmacopeial standards (USP, EP), it is free from irritants, allergens, and preservatives, making it suitable for prolonged use. Its stability is maintained in airtight, light-resistant packaging at room temperature (15-25°C).

Function:
1. Antifungal Action: Inhibits fungal sterol biosynthesis by targeting two key enzymes-sterol Δ14-reductase and Δ7-Δ8 isomerase-disrupting ergosterol production and compromising fungal cell membrane integrity.
2. Broad-Spectrum Activity: Effective against dermatophytes (e.g., Trichophyton spp.), yeasts (e.g., Candida spp.), and molds (e.g., Aspergillus spp.).
3. Dual Fungicidal/Fungistatic Effects: Kills active fungal cells and prevents spore germination depending on concentration.
4. Anti-Biofilm Activity: Reduces fungal adhesion and biofilm formation on nails and skin.
5. Long-Lasting Residual Effect: Sustains therapeutic concentrations in nails with once-weekly application.
6. Minimal Systemic Absorption: Acts locally with negligible systemic exposure, ensuring safety for long-term use.

Applications:
1. Onychomycosis Treatment:
Nail Lacquers: The Primary ingredient in medicated nail polish for fungal nail infections (e.g., 5% w/v formulations).
Nail Debridement Support: Softens and thins infected nails to enhance antifungal penetration.
2. Dermatophytosis Management:
Topical Creams/Gels: Treats tinea pedis (athlete's foot), tinea corporis (ringworm), and cutaneous candidiasis.
3. Preventive Care:
High-Risk Settings: Prophylactic use in athletes, diabetics, or immunocompromised individuals to prevent fungal colonization.
4. Veterinary Use:
Topical solutions for fungal infections in pets (e.g., canine onychomycosis).
5. Cosmetic Antifungal Products:
Incorporated into antifungal foot sprays, powders, or shoe inserts to combat odor and infection.
6. Combination Therapy:
Paired with oral antifungals (e.g., terbinafine) for refractory cases of nail or skin infections.

Amorolfine Hydrochloride is a cornerstone of topical antifungal therapy, offering a potent, patient-friendly solution for stubborn fungal infections. Its unique mechanism, low resistance potential, and compatibility with cosmetic formulations make it a preferred choice in dermatology, podiatry, and veterinary medicine.

 

 

 

Company Profile

FAQ

1. Are you a manufacturer or trading company?

A: We are a manufacturer and welcome to visit our factory.
 
2. How to confirm the product quality before placing an order?
A: We can provide you with the sample. Also, we have the inspection report issued by the authoritative third-party testing agency.
 
3: What's your MOQ?
A:  It depends on different products. We accept sample orders. Also for some products, we can provide you with a free sample.
 
4:Do you provide after-sales service?
A: We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us.
 
5:How about delivery time and method?
A: We usually ship within 3-5 working days after payments. 
We can make ships by sea, air, and express. Also can make door-to-door shipping. 
 
6:How to solve the after-sale disputes?
A: We accept changing or refunding services if there is any quality problem.