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Introduction:
Cyclosporine is a medication that belongs to the class of immunosuppressive drugs. It was first discovered in 1971 and has since been widely used in medical treatments. Cyclosporine is derived from a fungus called Tolypocladium inflatum, making it a naturally occurring compound with potent therapeutic properties.
Function:
Cyclosporine functions by suppressing the immune system's response, specifically targeting T-cells, which play a crucial role in immune activation. By inhibiting T-cell activation, cyclosporine helps to prevent the rejection of transplanted organs and treat autoimmune diseases, such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease.
Application:
Cyclosporine finds extensive application in the field of organ transplantation. It is used as an immunosuppressant to prevent organ rejection following kidney, liver, heart, and lung transplantation. Additionally, cyclosporine is utilized in the treatment of various autoimmune conditions, including severe plaque psoriasis, atopic dermatitis, and rheumatoid arthritis. Its effectiveness in managing these diseases has made it an invaluable medication in improving patients' quality of life.
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