Product Description:
Dutasteride is a synthetic 4-azasteroid compound that serves as a potent inhibitor of the enzyme 5-alpha-reductase. It is primarily used in the treatment of benign prostatic hyperplasia (BPH) and is available in capsule form. The chemical formula of dutasteride is C27H30F6N2O2, and it appears as a white to slightly yellow powder. Dutasteride is marketed under various brand names, including Avodart.
Function:
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5-Alpha-Reductase Inhibition: Dutasteride works by inhibiting both Type 1 and Type 2 isoforms of the enzyme 5-alpha-reductase, which converts testosterone into dihydrotestosterone (DHT). By reducing the levels of DHT, it helps decrease the size of the enlarged prostate gland.
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Reduction of Prostate Size: The reduction in DHT levels leads to a decrease in prostate volume, which helps alleviate the symptoms of benign prostatic hyperplasia, such as urinary frequency, urgency, and difficulty in urination.
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Hair Growth Promotion: Dutasteride is also studied for its potential in treating androgenetic alopecia (male pattern baldness) due to its ability to lower scalp DHT levels.
Application:
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Benign Prostatic Hyperplasia (BPH):
- Symptom Relief: Dutasteride is prescribed to treat BPH symptoms, improving urinary flow and reducing the need for surgery. It helps in relieving urinary retention and decreasing the risk of acute urinary retention.
- Long-Term Management: It is used for long-term management of BPH, helping to reduce prostate size and prevent the progression of the disease.
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Combination Therapy:
- With Alpha-Blockers: Dutasteride is often used in combination with alpha-blockers (e.g., tamsulosin) to enhance the therapeutic effects in treating BPH. This combination therapy provides both immediate and long-term symptom relief.
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Androgenetic Alopecia:
- Hair Loss Treatment: Dutasteride is being researched and used off-label for the treatment of male pattern hair loss. It works by reducing DHT levels in the scalp, which helps in promoting hair growth and preventing further hair loss.
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Research and Development:
- Pharmacological Studies: Dutasteride is used in clinical research to study its effects on androgen-dependent conditions, expanding the understanding of its therapeutic potential and side effect profile.
- New Formulations: Ongoing research aims to develop new formulations and delivery methods to improve the efficacy and patient compliance of dutasteride.
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Preventive Medicine:
- Prostate Cancer Risk Reduction: There is ongoing research into the potential role of dutasteride in reducing the risk of prostate cancer in high-risk individuals, given its effects on DHT levels and prostate size.
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Veterinary Medicine:
- Animal Health: Dutasteride is being explored for use in veterinary medicine to treat conditions related to hormonal imbalances in animals, particularly in managing symptoms of BPH in older male pets.
FAQ:
1. Are you a manufacturer or trading company?
A: We are a manufacturer and welcome to visit our factory.
2. How to confirm the product quality before placing an order?
A: We can provide you with the sample. Also, we have the inspection report issued by the authoritative third-party testing agency.
3: What's your MOQ?
A: It depends on different products. We accept sample orders. Also for some products, we can provide you with a free sample.
4:Do you provide after-sales service?
A: We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us.
5:How about delivery time and method?
A: We usually ship within 3-5 working days after payments.
We can make ships by sea, air, and express. Also can make door-to-door shipping.
6:How to solve the after-sale disputes?
A: We accept changing or refunding services if there is any quality problem.
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