High Quality Pharmaceutical Chemical Purity Degree 99% CAS No. 114977-28-5 Docetaxel

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Model NO.: Docetaxel
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Specification: 99%min by HPLC
• Trademark: Keynovo biotech
• Origin: China
• Production Capacity: 100kg Per Week

Product Description

Product Description:

Docetaxel is a semi-synthetic chemotherapeutic agent belonging to the taxane family, derived from the needles of the European yew tree (Taxus baccata). It is a white to almost-white crystalline powder with the molecular formula C43H53NO14 and a molecular weight of 807.88 g/mol. Docetaxel is widely used in oncology for its potent antineoplastic properties, making it a critical drug in the treatment of various cancers.

Function:

1. Antineoplastic Agent: Docetaxel works by inhibiting cell division, specifically during the mitotic phase, by promoting the assembly of microtubules and preventing their depolymerization. This action disrupts the normal function of microtubules, essential for cell division, thereby inhibiting the growth and spread of cancer cells.

2. Apoptosis Induction: It induces apoptosis (programmed cell death) in cancer cells by stabilizing microtubule formation, leading to cell cycle arrest and cell death.

3. Antiangiogenic Properties: Docetaxel exhibits antiangiogenic effects, meaning it can inhibit the formation of new blood vessels that tumors need to grow and metastasize.

Application:

1. Oncology:

   • Breast Cancer: Docetaxel is used as a first-line treatment for locally advanced or metastatic breast cancer, either alone or in combination with other chemotherapeutic agents.
   • Non-Small Cell Lung Cancer (NSCLC): It is administered in combination with other drugs for the treatment of NSCLC, particularly in patients who have failed prior platinum-based chemotherapy.
   • Prostate Cancer: Docetaxel, in combination with prednisone, is used for the treatment of metastatic castration-resistant prostate cancer.
   • Gastric Cancer: It is used in combination with other chemotherapeutic agents for the treatment of advanced gastric adenocarcinoma.
   • Head and Neck Cancer: Docetaxel is used in combination with cisplatin and fluorouracil for the treatment of locally advanced squamous cell carcinoma of the head and neck.

2. Research and Development:

   • Cancer Research: Docetaxel is widely used in preclinical and clinical research to study its mechanisms of action, resistance, and potential new therapeutic combinations.
   • Pharmaceutical Development: It is a key compound in the development of new formulations and delivery systems aimed at improving efficacy and reducing side effects.

3. Palliative Care:

   • Symptom Management: In advanced stages of cancer, Docetaxel is used to help manage symptoms and improve the quality of life for patients by slowing the progression of the disease.

4. Combination Therapy:

   • Chemotherapy Regimens: Docetaxel is often used in combination with other chemotherapeutic agents, targeted therapies, and immunotherapies to enhance therapeutic outcomes and overcome drug resistance.

5. Adjuvant and Neoadjuvant Therapy:

   • Preoperative Treatment: Docetaxel is used in neoadjuvant therapy to shrink tumors before surgical removal.
   • Postoperative Treatment: It is used in adjuvant therapy to eliminate any remaining cancer cells following surgery, reducing the risk of recurrence.

FAQ:

1. Are you a manufacturer or trading company?
A: We are a manufacturer and welcome to visit our factory.
 
2. How to confirm the product quality before placing an order?
A: We can provide you with the sample. Also, we have the inspection report issued by the authoritative third-party testing agency.
 
3: What's your MOQ?
A:  It depends on different products. We accept sample orders. Also for some products, we can provide you with a free sample.
 
4:Do you provide after-sales service?
A: We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us.
 
5:How about delivery time and method?
A: We usually ship within 3-5 working days after payments. 
We can make ships by sea, air, and express. Also can make door-to-door shipping. 
 
6:How to solve the after-sale disputes?
A: We accept changing or refunding services if there is any quality problem.