Factory Supply Pharmaceutical Ondansetron Powder CAS 99614-02-5

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Model NO.: Ondansetron
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Specification: USP
• Trademark: Keynovo biotech
• Origin: China
• Production Capacity: 100kg Per Week

Product Description

Product Description:

Ondansetron is a selective serotonin 5-HT3 receptor antagonist used primarily as an antiemetic to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It appears as a white to off-white crystalline powder and is available in various forms, including tablets, orally disintegrating tablets, oral solution, and injectable forms. The molecular formula of ondansetron is C18H19N3O.

Function:

1. Antiemetic Action: Ondansetron works by blocking serotonin receptors in the central nervous system and the gastrointestinal tract. This action prevents the activation of the vomiting reflex, making it effective in controlling nausea and vomiting.

2. Serotonin Receptor Antagonism: By selectively inhibiting the 5-HT3 receptors, ondansetron reduces the activity of the vagus nerve, which plays a significant role in inducing vomiting.

3. Fast Onset and Long Duration: Ondansetron is known for its rapid onset of action and sustained effect, providing extended relief from nausea and vomiting.

Application:

1. Cancer Treatment:

   • Chemotherapy-Induced Nausea and Vomiting (CINV): Ondansetron is extensively used to prevent nausea and vomiting in patients undergoing chemotherapy. It is administered prior to chemotherapy and continued for a few days post-treatment to ensure optimal control of symptoms.
   • Radiation Therapy-Induced Nausea and Vomiting: It is also effective in preventing nausea and vomiting caused by radiation therapy, improving the quality of life for patients undergoing cancer treatment.

2. Postoperative Nausea and Vomiting (PONV):

   • Surgical Procedures: Ondansetron is administered preoperatively or postoperatively to prevent and treat nausea and vomiting associated with surgical procedures. This application helps in faster recovery and reduces the risk of complications related to vomiting.

3. Gastroenteritis:

   • Acute Gastroenteritis: In cases of acute gastroenteritis, ondansetron is used to control severe nausea and vomiting, allowing patients to maintain hydration and reduce the risk of dehydration.

4. Hyperemesis Gravidarum:

   • Pregnancy-Related Nausea: Although used cautiously, ondansetron is sometimes prescribed for managing hyperemesis gravidarum, a severe form of nausea and vomiting during pregnancy, when other treatments are ineffective.

5. Off-Label Uses:

   • Alcohol Dependence: Ondansetron has been studied for its potential role in reducing alcohol cravings and consumption in individuals with alcohol dependence.
   • Pruritus Management: It is occasionally used off-label to manage severe itching (pruritus) associated with certain medical conditions.

6. Pediatric Use:

   • Children's Nausea and Vomiting: Ondansetron is used in pediatric patients to control nausea and vomiting due to chemotherapy, surgery, or gastroenteritis, ensuring better tolerance and recovery.

7. Palliative Care:

   • Symptom Relief: In palliative care settings, ondansetron is used to provide relief from nausea and vomiting associated with terminal illnesses, improving patient comfort and quality of life.

8. Research and Development:

   • Clinical Studies: Ondansetron continues to be a subject of research for its potential applications in various medical conditions and its effectiveness in combination therapies.

FAQ:

1. Are you a manufacturer or trading company?
A: We are a manufacturer and welcome to visit our factory.
 
2. How to confirm the product quality before placing an order?
A: We can provide you with the sample. Also, we have the inspection report issued by the authoritative third-party testing agency.
 
3: What's your MOQ?
A:  It depends on different products. We accept sample orders. Also for some products, we can provide you with a free sample.
 
4:Do you provide after-sales service?
A: We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us.
 
5:How about delivery time and method?
A: We usually ship within 3-5 working days after payments. 
We can make ships by sea, air, and express. Also can make door-to-door shipping. 
 
6:How to solve the after-sale disputes?
A: We accept changing or refunding services if there is any quality problem.