| Customization: | Available |
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| CAS No.: | 25249-54-1 |
| Formula: | C6h9no |
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Introduction to Crospovidone (PVPP):
Crospovidone, also known as polyvinylpolypyrrolidone or PVPP, is a highly cross-linked polymer used as a pharmaceutical excipient. Derived from polyvinylpyrrolidone (PVP), Crospovidone is renowned for its exceptional water absorption and rapid disintegration properties. This versatile excipient is widely employed in the pharmaceutical industry to improve the performance of various oral solid dosage forms.
Function of Crospovidone (PVPP) in Pharmaceutical Excipients:
The primary function of Crospovidone in pharmaceutical formulations is as a superdisintegrant and binder. As a superdisintegrant, Crospovidone exhibits rapid water absorption and swelling, leading to the quick disintegration of tablets or capsules upon contact with aqueous media. This property is particularly crucial for enhancing the dissolution and bioavailability of drugs. Additionally, Crospovidone serves as a binder, promoting the cohesion of powdered drug mixtures during tablet compression, ensuring the formation of tablets with optimal hardness and disintegration characteristics.
Application of Crospovidone (PVPP) in Pharmaceutical Formulations:
Crospovidone finds extensive application in the pharmaceutical industry, especially in the production of fast-dissolving tablets, chewable tablets, and orally disintegrating dosage forms. Its superdisintegrating properties make it an essential component for formulations where rapid disintegration and drug release are critical. Crospovidone is commonly used in combination with other excipients in tablet manufacturing processes to improve the overall quality and performance of the dosage form. Its compatibility with various drug formulations and its ability to enhance patient compliance by facilitating convenient and rapid drug administration make Crospovidone a valuable and widely utilized excipient in the pharmaceutical field.
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