| Customization: | Available |
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| Powder: | Yes |
| Certification: | GMP, HSE, ISO 9001, USP, BP |
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Product Description:
11α-Hydroxy Canrenone Methyl Ester is a compound derived from canrenone, which is a naturally occurring steroid hormone. It is a methyl ester derivative of 11α-hydroxy canrenone and possesses specific structural modifications. This compound is a white crystalline powder with a molecular formula C24H38O3.
Function:
11α-Hydroxy Canrenone Methyl Ester exhibits various biological activities and functions as a selective mineralocorticoid receptor antagonist. It specifically targets the corticoid receptors in the body, interfering with their activation by endogenous hormones like aldosterone. By acting as an antagonist, it blocks the effects of mineralocorticoids, which are involved in regulating electrolyte and fluid balance. This compound's function is crucial in the treatment of several health conditions related to mineralocorticoid receptor hyperactivity.
Application:
11α-Hydroxy Canrenone Methyl Ester finds application in the pharmaceutical industry, primarily as a pharmacological agent for treating and managing different disorders. Some notable applications include:
1. Hyperaldosteronism Treatment: Due to its mineralocorticoid receptor antagonist activity, this compound can be used to treat primary hyperaldosteronism, a condition characterized by excessive production of aldosterone. By blocking the receptor, it helps regulate electrolyte and fluid balance and manages associated symptoms.
2. Hypertension Management: In certain cases of hypertension, where elevated aldosterone levels contribute to increased blood pressure, 11α-Hydroxy Canrenone Methyl Ester can be utilized to counteract the effects of aldosterone. It aids in blood pressure control and prevention of complications associated with uncontrolled hypertension.
3. Congestive Heart Failure: This compound has shown potential in managing congestive heart failure by targeting the mechanisms involving aldosterone and mineralocorticoid receptors. By inhibiting excessive mineralocorticoid receptor activation, it helps mitigate the adverse effects on cardiac function.
4. Edema Treatment: As a mineralocorticoid receptor antagonist, 11α-Hydroxy Canrenone Methyl Ester can be employed to address edema (fluid retention) associated with certain medical conditions. It helps reduce fluid accumulation by regulating electrolyte balance and fluid excretion.
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