| Customization: | Available |
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| CAS No.: | Customization, 78214-41-2 |
| Formula: | Customization |
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Introduction to Low Substituted Hydroxypropyl Cellulose (L-HPC):
Low Substituted Hydroxypropyl Cellulose (L-HPC) is a derivative of cellulose, modified to enhance its solubility and functionality in various applications, particularly in the pharmaceutical industry. This semi-synthetic polymer has gained prominence as a pharmaceutical excipient due to its unique combination of water solubility and biocompatibility. L-HPC exhibits a low degree of substitution, distinguishing it from its more highly substituted counterparts, and finds versatile use in pharmaceutical formulations.
Function of L-HPC in Pharmaceutical Excipients:
L-HPC serves as a multifunctional pharmaceutical excipient with distinctive properties. Its primary function lies in its role as a binder in tablet formulations. By imparting cohesiveness to powdered drug mixtures, L-HPC facilitates the compression process, resulting in tablets with improved mechanical strength and integrity. Additionally, L-HPC functions as a disintegrant, promoting the rapid disintegration of tablets in aqueous media, thereby facilitating drug release. Its water-soluble nature allows for easy incorporation into various dosage forms without compromising the dissolution characteristics of the active pharmaceutical ingredients.
Application of L-HPC in Pharmaceutical Formulations:
In pharmaceutical formulations, L-HPC finds wide-ranging applications, contributing to the development of tablets, capsules, and other dosage forms. As a binder, L-HPC enhances the tabletting process by ensuring uniformity and strength. Its compatibility with different drug formulations makes it suitable for a variety of therapeutic compounds. L-HPC's disintegrating properties make it invaluable in the production of fast-disintegrating tablets, ensuring quick drug release and enhanced patient compliance. Moreover, L-HPC is employed in the preparation of oral solid dosage forms where rapid disintegration and dissolution are critical factors for therapeutic efficacy. The adaptability and functionality of L-HPC position it as a versatile and essential excipient in modern pharmaceutical formulations.
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