Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Description:
Poloxamer 407, also known as Pluronic F127, is a triblock copolymer composed of polyoxyethylene and polypropylene. This versatile nonionic surfactant is known for its excellent solubilizing, emulsifying, and stabilizing properties. Poloxamer 407 is widely used in pharmaceuticals, personal care products, and industrial applications due to its unique characteristics and high safety profile. Our high-purity Poloxamer 407 is manufactured to meet the highest standards, ensuring optimal performance in all formulations.
Function:
Solubilizing Agent: Poloxamer 407 is effective in solubilizing hydrophobic compounds, enhancing the bioavailability of poorly soluble drugs and active ingredients.
Emulsifier: It acts as an emulsifying agent, helping to create stable emulsions of oil and water. This is essential in various formulations, from pharmaceuticals to cosmetics.
Stabilizer: Poloxamer 407 stabilizes formulations by preventing the separation of ingredients and maintaining the homogeneity of the product.
Thermoreversible Gelation: It exhibits thermoreversible gelation properties, forming a gel at body temperature and returning to a liquid state at cooler temperatures. This makes it ideal for controlled drug delivery systems.
Nonionic Surfactant: As a nonionic surfactant, Poloxamer 407 is mild and non-irritating, suitable for sensitive applications, including ophthalmic and dermal formulations.
Application:
Pharmaceuticals: Poloxamer 407 is used in pharmaceutical formulations as a solubilizer, emulsifier, and stabilizer. It is particularly useful in controlled-release drug delivery systems, topical gels, and injectable formulations.
Personal Care Products: It is widely used in personal care products, including shampoos, conditioners, body washes, and lotions. Poloxamer 407 enhances the texture, stability, and performance of these products.
Cosmetics: In cosmetics, Poloxamer 407 is used to create smooth and stable formulations. It helps in the emulsification of creams and lotions and enhances the sensory properties of makeup products.
Ophthalmic Solutions: Poloxamer 407 is used in eye drops and other ophthalmic solutions for its non-irritating properties and ability to form clear, stable solutions.
Industrial Applications: It is utilized in industrial applications such as detergents, cleaning agents, and coatings for its emulsifying and stabilizing properties.
Biomedical Applications: Poloxamer 407 is employed in biomedical applications, including tissue engineering, wound care products, and as a component in hydrogel-based drug delivery systems.