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Introduction to Soluble Starch:
Soluble Starch is a modified form of starch obtained through chemical or enzymatic processes, resulting in a product with improved solubility in water. This carbohydrate polymer, derived from natural sources like corn, wheat, or potatoes, finds application in various industries, including pharmaceuticals. Soluble Starch's distinctive solubility characteristics make it a valuable pharmaceutical excipient, contributing to the development of formulations with specific functional requirements.
Function of Soluble Starch in Pharmaceutical Excipients:
The primary function of Soluble Starch in pharmaceutical formulations is as a binder, thickening agent, and stabilizer. As a binder, Soluble Starch enhances the cohesion of powdered drug mixtures during tablet compression, ensuring the formation of tablets with desirable hardness and disintegration properties. Its role as a thickening agent is evident in liquid formulations, where it imparts viscosity, stabilizing suspensions and emulsions. Furthermore, Soluble Starch can function as a stabilizer, contributing to the stability of certain pharmaceutical formulations, especially those prone to degradation or settling.
Application of Soluble Starch in Pharmaceutical Formulations:
Soluble Starch is widely employed in the pharmaceutical industry, notably in the production of tablets, capsules, and liquid formulations. In tablet manufacturing, it serves as a binder, facilitating the compression of powdered drug blends into cohesive tablets. Soluble Starch is also utilized in liquid formulations, such as oral suspensions and syrups, where its thickening properties contribute to the desired viscosity and stability of the formulation. Additionally, Soluble Starch may find application in topical formulations, contributing to the rheological properties of creams and gels. Its versatility and compatibility with various drug formulations make Soluble Starch a valuable excipient in pharmaceutical development.
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