Customization: | Available |
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CAS No.: | 9003-11-6 |
Formula: | Ho.(C2h4o)M.(C3h6o)N.H |
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Product Description:
Poloxamer 188 is a non-ionic triblock copolymer consisting of PEO-PPO-PEO chains. It is a clear, viscous liquid at room temperature with a low toxicity profile. Poloxamer 188 is widely used in various industries for its unique properties and excellent solubilizing capabilities.
Function:
Poloxamer 188 functions as a surfactant, emulsifier, and solubilizer. Its amphiphilic nature allows it to lower the surface tension of liquids, enabling it to disperse and stabilize emulsions. It also acts as a solubilizer, increasing the solubility of hydrophobic substances in aqueous solutions. Additionally, Poloxamer 188 can form gels when heated and undergoes reversible gel-sol transitions, making it useful in pharmaceutical and biomedical applications.
Application:
Poloxamer 188 finds applications in various industries due to its versatile properties. Some of its key applications include:
1. Pharmaceutical Industry: Poloxamer 188 is widely utilized in pharmaceutical formulations as a solubilizer and stabilizer. It helps enhance the solubility of poorly water-soluble drugs and improves their bioavailability. Furthermore, it is also used as a cryoprotectant and cell membrane stabilizer in the storage and transportation of sensitive biological materials.
2. Cosmetics and Personal Care Products: Poloxamer 188 is employed in cosmetic and personal care formulations for its emulsifying and stabilizing properties. It is often used in lotions, creams, and gels to improve texture, provide long-lasting stability, and enhance product performance.
3. Food and Beverage Industry: Poloxamer 188 is utilized as an emulsifier and stabilizer in food and beverage products. It helps create stable emulsions, improves mouthfeel, and enhances the overall texture of various food and beverage formulations.
4. Industrial Applications: Poloxamer 188 is employed in various industrial applications, such as paints, coatings, and lubricants. It acts as a dispersing agent, assisting in the uniform distribution of pigments and other additives. Additionally, it can also be used as a cleaning agent in certain industrial processes.
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