Customization: | Available |
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CAS No.: | Customs, Customs |
Formula: | Customs, Customs |
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Introduction:
Palbociclib Powder, with the chemical name 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, is a potent and selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). It is a white crystalline powder that is soluble in organic solvents.
Function:
Palbociclib Powder acts by specifically inhibiting the activity of CDK4/6, which play a crucial role in cell cycle progression and tumor growth. By blocking CDK4/6, Palbociclib prevents the G1 to S phase transition in cancer cells, thereby inhibiting their proliferation. This targeted inhibition helps to control the growth of cancer cells and potentially halt the progression of the disease.
Application:
Palbociclib Powder is primarily used in the treatment of hormone receptor-positive (HR+), Palbociclib has shown significant clinical benefits, including improved progression-free survival and overall response rates, making it a valuable treatment option for patients with advanced breast cancer.
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