| Customization: | Available |
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| CAS No.: | Customization, 128270-60-0 |
| Formula: | Customization |
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Introduction:
Bivalirudin, also known as Bivalirudin Trifluoroacetate, is a synthetic peptide drug used as an anticoagulant in medical settings. With a molecular weight of 2180 Daltons, it is a direct thrombin inhibitor that works by binding to both circulating and clot-bound thrombin, preventing the conversion of fibrinogen to fibrin and thus inhibiting blood clot formation.
Function:
Bivalirudin is highly effective in preventing blood coagulation and is primarily used during percutaneous coronary intervention (PCI) procedures, such as balloon angioplasty or stent placement, in patients with acute coronary syndromes. It is administered intravenously and is often combined with aspirin and/or other antiplatelet drugs to achieve optimal anticoagulation and ensure procedural success.
In terms of its efficacy, Bivalirudin has shown superiority over alternative anticoagulants in reducing the risk of major adverse cardiac events, including myocardial infarction and stent thrombosis, while maintaining a lower incidence of bleeding complications. This makes it a preferred option in patients with a high risk of bleeding or those undergoing complex interventions.
Application:
Apart from its use in PCI, Bivalirudin has also demonstrated efficacy in the management of heparin-induced thrombocytopenia, a serious immune-mediated disorder characterized by low platelet counts and increased risk of thrombosis. Its unique mechanism of action makes it a valuable alternative to heparin in these cases.
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