Pharmaceutical Intermediates N-Boc-Piperazine CAS 57260-71-6

• CAS No.: 57260-71-6
• Formula: C9h18n2o2
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Technical
• Colour: White
• Model NO.: N-BOC-piperazine
• MOQ: 1 Kilograms
• Storage: Cool Dry Place
• Package: 1kg/ Bag 25kg/Drum
• Purity: 90%-99.99%
• Delivery Time: 15-25 Days
• Grade: Mecical Grade
• Use: Medicine
• Place of Origin: Anhui, China
• Advantage: Fctory & Professional
• Brand Name: Keynovo
• Shelf Life: 2 Years
• Sample: Avaliable
• Usage: Usage Raw Materials
• Transport Package: Drum
• Specification: 25kg/drum
• Trademark: keynovo
• Origin: China
• Production Capacity: 10000 Kg Per Week

Product Description

Products Description

N-BOC-piperazine, also known as t-butoxycarbonyl piperazine, is a chemical compound that belongs to the piperazine family. It is derived from piperazine by attaching a t-butoxycarbonyl (BOC) group to the nitrogen atom. This modification enhances the compound's stability and introduces various functional groups for further chemical reactions. N-BOC-piperazine is widely used in organic synthesis and pharmaceutical research due to its versatile properties and applications.

Function

N-BOC-piperazine serves as a protecting group in organic synthesis, particularly in peptide and drug synthesis. By temporarily blocking the reactivity of the amino group in piperazine, it enables selective chemical transformations and controls the reaction outcome. The BOC group can be easily removed under mild conditions, allowing the restored functionality of the piperazine moiety.

Application

1. Peptide Synthesis: N-BOC-piperazine plays a vital role in solid-phase peptide synthesis (SPPS). It acts as a protecting group for the amino group of an amino acid during peptide chain assembly. The BOC group ensures the specificity of the reaction, prevents unwanted side reactions, and facilitates the stepwise elongation of the peptide chain. Once synthesis is complete, the BOC group can be removed to reveal the active amino group for further modifications or cleavage from the solid support.
    

2. Drug Development: N-BOC-piperazine is extensively used in medicinal chemistry and drug development. It serves as a key building block for the synthesis of various pharmaceutical compounds, including antipsychotics, antihistamines, and antiviral drugs. The BOC group provides steric protection to specific functional groups, enabling the creation of novel drug candidates with improved selectivity, solubility, and bioavailability.

FAQ:

1. Are you a manufacturer or trading company?
A: We are a manufacturer and welcome to visit our factory.
 
2. How to confirm the product quality before placing an order?
A: We can provide you with the sample. Also, we have the inspection report issued by the authoritative third-party testing agency.
 
3: What's your MOQ?
A:  It depends on different products. We accept sample orders. Also for some products, we can provide you with a free sample.
 
4:Do you provide after-sales service?
A: We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us.
 
5:How about delivery time and method?
A: We usually ship within 3-5 working days after payments. 
We can make ships by sea, air, and express. Also can make door-to-door shipping. 
 
6:How to solve the after-sale disputes?
A: We accept changing or refunding services if there is any quality problem.