| Customization: | Available |
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| CAS No.: | Customs, Customs |
| Formula: | Customs, Customs |
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Introduction:
Dasatinib monohydrate is a pharmaceutical compound that belongs to the class of tyrosine kinase inhibitors (TKIs). It is commonly used in the treatment of certain types of leukemia, including chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). Dasatinib monohydrate is formulated as a monohydrate salt, which enhances its stability and ease of handling in pharmaceutical preparations.
Function:
Dasatinib monohydrate works by selectively inhibiting the activity of specific tyrosine kinases, such as BCR-ABL, SRC family kinases, and receptor tyrosine kinases. By inhibiting the activity of these kinases, dasatinib monohydrate blocks the signaling pathways that promote the growth and proliferation of cancer cells. This leads to the suppression of tumor growth and helps to control the progression of leukemia.
Application:
Treatment of Chronic Myeloid Leukemia (CML): Dasatinib monohydrate is a highly effective treatment option for patients with CML, particularly those who are resistant or intolerant to other therapies, such as imatinib. It is often prescribed as a frontline therapy or as a second-line treatment for CML.
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