CAS No.: | 503070-58-4 |
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Formula: | C44h49cl2no7 |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Quality: | Technical |
Colour: | White |
Samples: |
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Customization: |
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Vilanterol functions as a selective agonist for the beta2-adrenergic receptors in the smooth muscles of the airways. When administered via inhalation, it binds to these receptors, activating them and leading to smooth muscle relaxation. This relaxation allows the airways to widen, facilitating increased airflow and improved breathing.
By promoting bronchodilation, vilanterol helps alleviate bronchospasms and reduces airway resistance, making it easier for individuals with respiratory conditions to breathe. Its long-acting nature allows for sustained relief over an extended period, typically up to 24 hours after administration, which contributes to its convenience and effectiveness as a maintenance treatment.
Furthermore, vilanterol's specific targeting of the beta2-adrenergic receptors helps minimize systemic side effects, maximizing its therapeutic benefits while minimizing unwanted effects on other parts of the body.
ApplicationVilanterol is primarily used as a maintenance treatment for patients with COPD and asthma. It is typically prescribed as part of a combination therapy, alongside an inhaled corticosteroid (ICS), to provide comprehensive symptom control. By combining a LABA like vilanterol with an ICS, patients can benefit from both the bronchodilatory effects of the LABA and the anti-inflammatory properties of the corticosteroid. This combination approach helps to reduce inflammation, open up the airways, and improve lung function.
In addition to its role in COPD and asthma management, vilanterol has also found application in the field of exercise-induced bronchoconstriction (EIB) prevention. By using vilanterol prior to physical activity, individuals with EIB can experience improved exercise tolerance and decreased respiratory symptoms, enabling them to participate in physical exertion with greater ease.
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