Products Description
| Product name:Cilastatin sodium |
| Other Name:Cilastatin Sodium Salt |
| Appearance:White Powder |
| CAS:81129-83-1 |
| M.F:C16H25N2O5S.Na |
| M W:380.44 |
| Grade:Pharmaceutical Grade |
| Specification:99% |
The monosodium salt of cilastatin. It is an inhibitor of dehydropeptidase I (membrane dipeptidase, 3.4.13.19), an enzyme found in the brush border of renal tubes and responsible for degrading the antibiotic imipenem. Cilastatin sodium is therefore administ red with imipenem to prolong the antibacterial effect of the latter by preventing its renal metabolism to microbiologically inactive and potentially nephrotoxic products.
Biological ActivityDipeptidase inhibitor (LTDase, leukotriene D4 hydrolase, dehydropeptidase I) that displays a K i value of 0.11 μ M. Inhibits metabolism of LTD 4 to LTE 4 and the hydrolysis of β -lactam antibiotics. Nephroprotective; reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells.
| Shipping Method |
FedEx/DHL/TNT |
Shipping by Air |
Shipping by Sea |
| Suitable Quantity |
Under 25KG |
Under 100KG |
More Than 100KG |
| Shipment Time |
3-10 Days |
5-15 Days |
15-45 Days |
| Shipping Cost |
High Cost |
High Cost |
Lost Cost |
| Service |
Door to Door |
Door to Airport |
Port to Port |
| Other |
Easy to Pick Up Goods |
Professional Broker is Needed |
FAQ
1. Are you a manufacturer or trading company?
A: We are a manufacturer and welcome to visit our factory.
2. How to confirm the product quality before placing an order?
A: We can provide you with the sample. Also, we have the inspection report issued by the authoritative third-party testing agency.
3: What's your MOQ?
A: It depends on different products. We accept sample orders. Also for some products, we can provide you with a free sample.
4:Do you provide after-sales service?
A: We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us.
5:How about delivery time and method?
A: We usually ship within 3-5 working days after payments.
We can make ships by sea, air, and express. Also can make door-to-door shipping.
6:How to solve the after-sale disputes?
A: We accept changing or refunding services if there is any quality problem.
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