Medical Application Hypromellose Acetate Succinate

• CAS No.: 71138-97-1
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Technical
• Colour: White
• MOQ: 1 Kilograms
• Model NO.: Hypromellose Acetate Succinate
• Storage: Cool Dry Place
• Package: 1kg/ Bag 25kg/Drum
• Purity: 90%-99.99%
• Delivery Time: 15-25 Days
• Grade: Mecical Grade
• Use: Medicine
• Place of Origin: Anhui, China
• Advantage: Fctory & Professional
• Brand Name: Keynovo
• Shelf Life: 2 Years
• Sample: Avaliable
• Usage: Usage Raw Materials
• Transport Package: Safe Packing
• Specification: 25kg/drum
• Trademark: keynovo
• Origin: China
• Production Capacity: 10000 Kg Per Week

Product Description

Introduction to Hypromellose Acetate Succinate:

Hypromellose Acetate Succinate (HPMCAS) is a derivative of hypromellose, characterized by its unique chemical structure that combines acetate and succinate functionalities. This semi-synthetic polymer has garnered significant attention in the pharmaceutical industry, offering a range of applications owing to its solubility and pH-dependent properties. As a versatile excipient, HPMCAS plays a crucial role in drug formulation, particularly in the development of oral dosage forms.

Function of HPMCAS in Pharmaceutical Excipients:

In pharmaceutical excipients, HPMCAS serves as a multifunctional ingredient with notable functionalities. One key function is its role as a enteric coating agent. Due to its pH-dependent solubility, HPMCAS dissolves in the alkaline environment of the small intestine, providing a protective coating for acid-sensitive drugs, preventing their premature release in the stomach. Additionally, HPMCAS acts as a stabilizer for amorphous solid dispersions, enhancing the solubility and bioavailability of poorly water-soluble drugs. Its compatibility with a variety of active pharmaceutical ingredients makes it an attractive choice for formulators seeking to improve drug delivery profiles.

Application of HPMCAS in Pharmaceutical Formulations:

The applications of HPMCAS extend to various pharmaceutical formulations, contributing to the development of advanced drug delivery systems. In the production of delayed-release tablets, HPMCAS is employed as an enteric coating to protect drugs from the acidic gastric environment. This is particularly crucial for drugs that may cause irritation or degradation in the stomach. Furthermore, HPMCAS finds utility in the preparation of solid dispersions, enhancing the dissolution rates of poorly soluble drugs. Its versatility allows formulators to tailor drug release profiles and improve the overall therapeutic efficacy of pharmaceutical formulations. HPMCAS's adaptability to different formulation techniques positions it as a valuable tool for optimizing drug delivery.

 

 

 

 

 

 

FAQ

1. Are you a manufacturer or trading company?

A: We are a manufacturer and welcome to visit our factory.
 
2. How to confirm the product quality before placing an order?
A: We can provide you with the sample. Also, we have the inspection report issued by the authoritative third-party testing agency.
 
3: What's your MOQ?
A:  It depends on different products. We accept sample orders. Also for some products, we can provide you with a free sample.
 
4:Do you provide after-sales service?
A: We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us.
 
5:How about delivery time and method?
A: We usually ship within 3-5 working days after payments. 
We can make ships by sea, air, and express. Also can make door-to-door shipping. 
 
6:How to solve the after-sale disputes?
A: We accept changing or refunding services if there is any quality problem.